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Found 4 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid type B receptor subunit 1/2' and Ligand = 'BDBM50032964'
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair