BDBM50399538 BAY-579352::CHEMBL2079588

SMILES CNC(=O)c1cc(COc2nnc(Nc3ccc(Cl)cc3)c3ccoc23)ccn1

InChI Key InChIKey=QFCXANHHBCGMAS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50399538   

TargetMast/stem cell growth factor receptor Kit(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Progentos Therapeutics

US Patent
LigandPNGBDBM50399538(BAY-579352 | CHEMBL2079588 | US20250129067, Compou...)
Affinity DataIC50: 68.8nMAssay Description:The PDGFRα enzyme assays were conducted per the manufacturer's directions (Promega PDGFRα Kinase Enzyme System and ADP Glo Assay Cat #V8011). Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent