BDBM120390 US8703771, 3

SMILES Cc1ccc(NC(=O)c2ccc3C(CCc3c2)N2CCNCC2)cc1Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=SZPKERXOPUWUPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 120390   

TargetTyrosine-protein kinase ABL1(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120390(US8703771, 3)
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120390(US8703771, 3)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120390(US8703771, 3)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent