BDBM120398 US8703771, 11

SMILES CN1CCN(CC1)[C@H]1CCc2cc(ccc12)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=YTHUQGIGAIZNIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 120398   

TargetTyrosine-protein kinase ABL1(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120398(US8703771, 11)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120398(US8703771, 11)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120398(US8703771, 11)
Affinity DataIC50: 9.60nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent