BDBM14846 1-(3-tert-butyl-1-cyclohexyl-1H-pyrazol-5-yl)-3-[4-(2-morpholin-4-ylethoxy)-1-naphthyl]urea::3-(3-tert-butyl-1-cyclohexyl-1H-pyrazol-5-yl)-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB-796 Analog 36

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)n(n1)C1CCCCC1

InChI Key InChIKey=NKFKNLAAVAGPER-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14846   

TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14846(1-(3-tert-butyl-1-cyclohexyl-1H-pyrazol-5-yl)-3-[4...)
Affinity DataKd:  23nMpH: 7.0 T: 2°CAssay Description:UV thermal melt experiments were carried out in a quartz cuvette loaded with sample containing enzyme and each test compound using a spectrophotomete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed