BDBM16215 4-phenyl-1H-pyrazole::CHEMBL390066::JMC514968 Compound 35::pyrazole-based inhibitor 5
SMILES c1n[nH]cc1-c1ccccc1
InChI Key InChIKey=GPGKNEKFDGOXPO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 16215
Affinity DataIC50: 1.35E+5nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astex Therapeutics
Curated by ChEMBL
Astex Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of protein kinase BMore data for this Ligand-Target Pair
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair