BDBM16215 4-phenyl-1H-pyrazole::CHEMBL390066::JMC514968 Compound 35::pyrazole-based inhibitor 5

SMILES c1n[nH]cc1-c1ccccc1

InChI Key InChIKey=GPGKNEKFDGOXPO-UHFFFAOYSA-N

Data  2 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16215   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16215(4-phenyl-1H-pyrazole | CHEMBL390066 | JMC514968 Co...)
Affinity DataIC50:  1.35E+5nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM16215(4-phenyl-1H-pyrazole | CHEMBL390066 | JMC514968 Co...)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibition of protein kinase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM16215(4-phenyl-1H-pyrazole | CHEMBL390066 | JMC514968 Co...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed