BDBM195564 (2E)-2-(1H-Pyrrol-2-ylmethylidene)-2,3-dihydro-1H-inden-1-one (11j)::(2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-inden-1- one (11k)

SMILES O=C1\C(Cc2ccccc12)=C\c1ccc[nH]1

InChI Key InChIKey=YQKHTAYRNHDUJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195564   

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM195564((2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-i...)
Affinity DataIC50: 322nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM195564((2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-i...)
Affinity DataIC50: 379nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed