BDBM197710 US9216981, 39

SMILES Cc1nc2ccc(S(=O)(=O)Nc3ccc(F)c(Nc4ncccc4-c4ncnc5[nH]cnc45)c3F)cc2s1

InChI Key InChIKey=JPSGNCLLQOXYGW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197710   

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandChemical structure of BindingDB Monomer ID 197710BDBM197710(US9216981, 39)
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandChemical structure of BindingDB Monomer ID 197710BDBM197710(US9216981, 39)
Affinity DataEC50:  2.93E+3nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent