BDBM197710 US9216981, 39

SMILES Cc1nc2ccc(cc2s1)S(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F

InChI Key InChIKey=JPSGNCLLQOXYGW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197710   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197710(US9216981, 39)
Affinity DataEC50:  2.93E+3nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197710(US9216981, 39)
Affinity DataIC50:  400nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent