BDBM21072 Aminobenzoisoxazole, 9::[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]urea

SMILES NC(=O)Nc1ccc(cc1)-c1cccc2onc(N)c12

InChI Key InChIKey=QKEZZTSUDGCSDM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21072   

TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM21072([4-(3-amino-1,2-benzoxazol-4-yl)phenyl]urea | Amin...)
Affinity DataIC50: 619nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM21072([4-(3-amino-1,2-benzoxazol-4-yl)phenyl]urea | Amin...)
Affinity DataIC50: 4.44E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM21072([4-(3-amino-1,2-benzoxazol-4-yl)phenyl]urea | Amin...)
Affinity DataIC50: 1.25E+4nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2008
Entry Details Article
PubMed