BDBM224650 3-[6-{[(1r)-1- cyclobutylethyl]amino}-7- [(trans-4- methylcyclohexyl)methyl]- 8-(phenylsulfanyl)-7h- purin-2-yl]-1,2,4- oxadiazol-5(4h)-one::US9540377, 19.1
SMILES C[C@@H](Nc1nc(nc2nc(Sc3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)-c1noc(=O)[nH]1)C1CCC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224650
Affinity DataIC50: 0.763nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair