BDBM25387 7-[(2Z)-3-chlorobut-2-en-1-yl]-3-methyl-8-[(2Z)-2-[1-(4-nitrophenyl)ethylidene]hydrazin-1-yl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione::purine-2,6-dione, 30

SMILES C/C(Cl)=C/Cn1c(N=NC(C)c2ccc([N+](=O)[O-])cc2)nc2c1c(=O)[nH]c(=O)n2C

InChI Key InChIKey=CAKPSZHPTYIVEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25387   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Pennsylvania

LigandChemical structure of BindingDB Monomer ID 25387BDBM25387(7-[(2Z)-3-chlorobut-2-en-1-yl]-3-methyl-8-[(2Z)-2-...)
Affinity DataIC50: 1.74E+4nMpH: 7.0 T: 2°CAssay Description:BRAF kinase activity was quantified using an ELISA-based MEK phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curve f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed