BDBM25387 7-[(2Z)-3-chlorobut-2-en-1-yl]-3-methyl-8-[(2Z)-2-[1-(4-nitrophenyl)ethylidene]hydrazin-1-yl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione::purine-2,6-dione, 30

SMILES CC(N=Nc1nc2n(C)c(=O)[nH]c(=O)c2n1C\C=C(\C)Cl)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=CAKPSZHPTYIVEW-UHKNWHIESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25387   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM25387(7-[(2Z)-3-chlorobut-2-en-1-yl]-3-methyl-8-[(2Z)-2-...)
Affinity DataIC50:  1.74E+4nMpH: 7.0 T: 2°CAssay Description:BRAF kinase activity was quantified using an ELISA-based MEK phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curve f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed