BDBM258235 US9493448, 142::US9845313, Example 142

SMILES Cn1nccc1[C@@H]1CCCC[C@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=OJKONCJPCULNOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 258235   

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50: 4.70E+4nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50: 4.70E+4nMAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent