BDBM258235 US9493448, 142::US9845313, Example 142

SMILES Cn1nccc1[C@@H]1CCCC[C@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=OJKONCJPCULNOW-SUMWQHHRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 258235   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50:  4.70E+4nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel subunit beta-2(Homo sapiens)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50:  4.70E+4nMAssay Description:Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent