BDBM26705 7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H,4H,9H-quinolino[2,3-c][1,2]oxazole-3,4-dione::Isoxazoloquinolinedione, 13

SMILES CCn1c2n(CCO)oc(=O)c2c(=O)c2cc(F)c(Cl)cc12

InChI Key InChIKey=LGMKUVDUTQHORU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26705   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM26705(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Affinity DataKi:  1.16E+3nM ΔG°:  -8.01kcal/molepH: 7.5 T: 22°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM26705(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Affinity DataKi: >1.42E+3nM ΔG°: >-7.89kcal/molepH: 7.5 T: 22°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed