BDBM27890 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}amino)-5-oxo-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxamide::Pyrido[2,3-d]pyrimidin-5-one, 17a
SMILES CN1CCN(CCc2ccc(Nc3ncc4c(n3)n(cc(C(N)=O)c4=O)-c3ccc4CCCc4c3)cc2)CC1
InChI Key InChIKey=KLHJDCUHOKZNOP-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 27890
Affinity DataIC50: 0.800nMpH: 7.5 T: 22°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMT: 25°CAssay Description:FLT-3 was assayed using a fluorescence polarization (FP) competition immunoassay that measured FLT-3 phosphorylation of polyGlu4Tyr. The reaction was...More data for this Ligand-Target Pair
Affinity DataIC50: >500nMT: 25°CAssay Description:Axl was assayed using a fluorescence polarization (FP) competition immunoassay that measured Axl phosphorylation of polyGlu4Tyr. The reaction was ini...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of ATP-induced CSF1R autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMT: 25°CAssay Description:KIT was assayed using a fluorescence polarization (FP) competition immunoassay that measured KIT phosphorylation of polyGlu4Tyr. The reaction was ini...More data for this Ligand-Target Pair
Affinity DataIC50: >4.20E+4nMT: 25°CAssay Description:IRKbeta was assayed using a fluorescence polarization (FP) competition immunoassay that measured IRKbeta phosphorylation of polyGlu4Tyr. The reaction...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMT: 25°CAssay Description:TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i...More data for this Ligand-Target Pair