BDBM28281 1,3,4-oxadiazole substituted naphthyridine, 49::2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl}-8-hydroxy-1,6-naphthyridin-5-yl)-N-methylbenzene-1-sulfonamide

SMILES CNS(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12

InChI Key InChIKey=GGIXDBQCHGYSDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28281   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28281(1,3,4-oxadiazole substituted naphthyridine, 49 | 2...)
Affinity DataIC50:  4nMAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed