BDBM28304 1,3,4-oxadiazole substituted naphthyridine, 77::7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl}-5-[(4-hydroxypiperidin-1-yl)carbonyl]-1,6-naphthyridin-8-ol

SMILES OC1CCN(CC1)C(=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12

InChI Key InChIKey=PZGRCTPPFRAWNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28304   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28304(1,3,4-oxadiazole substituted naphthyridine, 77 | 7...)
Affinity DataIC50:  27nMAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed