BDBM32458 piperazine amide, 4e::piperazine amide, 6a

SMILES Clc1cccc(NC(=O)c2ccc(Br)o2)c1N1CCN(CC=C)CC1

InChI Key InChIKey=DZCSIYOZJRMQKN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32458   

TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM32458(piperazine amide, 6a | piperazine amide, 4e)
Affinity DataIC50: 240nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandPNGBDBM32458(piperazine amide, 6a | piperazine amide, 4e)
Affinity DataIC50: 330nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM32458(piperazine amide, 6a | piperazine amide, 4e)
Affinity DataIC50: 380nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
LigandPNGBDBM32458(piperazine amide, 6a | piperazine amide, 4e)
Affinity DataIC50: 1.26E+3nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed