BDBM331674 Preparation of 2-(2-fluoro-4-(7-methoxy-6-(2-morpholinoethoxy)quinoxalin-2-yl)phenyl)-N-(3-(1-methylcyclopropyl)isoxazol-5-yl)acetamide::US9725465, Example 95

SMILES COc1cc2nc(cnc2cc1OCCN1CCOCC1)-c1ccc(CC(=O)Nc2cc(no2)C2(C)CC2)c(F)c1

InChI Key InChIKey=UHPJTSMSMPTHLM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331674   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ambit Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 331674BDBM331674(US9725465, Example 95 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Ambit Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 331674BDBM331674(US9725465, Example 95 | Preparation of 2-(2-fluoro...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent