BDBM34071 benzamide derivative, 6

SMILES Cn1ccnc1Sc1cc(C(=O)Nc2nccs2)c(N)cc1F

InChI Key InChIKey=YUCYMQBDBXVNCE-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34071   

TargetGlycogen phosphorylase, muscle form(Rabbit)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataIC50:  4.39E+4nMpH: 7.2 T: 22°CAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHexokinase-4(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataKd:  360nMAssay Description:Binding affinity to human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluorometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetHexokinase-4(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM34071(benzamide derivative, 6)
Affinity DataEC50:  67.1nMAssay Description:The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)