BDBM342215 4-[4-[4-(4-methyl-5-phenyl-1H- imidazol-2-yl)-1-piperidyl]-7H- pyrrolo[2,3-d]pyrimidin-6- yl]benzonitrile::US9771369, Compound P-3047

SMILES Cc1nc([nH]c1-c1ccccc1)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N

InChI Key InChIKey=RAVSXLYICSPJMA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342215   

LigandPNGBDBM342215(4-[4-[4-(4-methyl-5-phenyl-1H- imidazol-2-yl)-1-pi...)
Affinity DataKi:  500nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM342215(4-[4-[4-(4-methyl-5-phenyl-1H- imidazol-2-yl)-1-pi...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent