BDBM36512 CID164227::Cylcophellitol, 3::US11826435, Compound 1.3

SMILES OC[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=YQLWKYQDOQEWRD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36512   

TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36512(CID164227 | Cylcophellitol, 3 | US11826435, Compou...)
Affinity DataKi:  152nM ΔG°:  -9.67kcal/mole IC50: 150nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36512(CID164227 | Cylcophellitol, 3 | US11826435, Compou...)
Affinity DataKi:  152nMAssay Description:Inactivation solutions contained a final concentration of 16.55 nM of Cerezyme (Recombinant GCase) in 200 μL of Reaction Buffer (50 mM acetate, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2024
Entry Details
US Patent