BDBM368998 N-[4-[6,7-bis(2- methoxyethoxy)quinazolin-4-yl]-3- fluoro-phenyl]-4-methoxy- benzenesulfonamide::US10227357, Compound P-0262

SMILES COCCOc1cc2ncnc(-c3ccc(NS(=O)(=O)c4ccc(OC)cc4)cc3F)c2cc1OCCOC

InChI Key InChIKey=ZKBJGPDYKGYEHO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368998   

LigandPNGBDBM368998(US10227357, Compound P-0262 | N-[4-[6,7-bis(2- met...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM368998(US10227357, Compound P-0262 | N-[4-[6,7-bis(2- met...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent