BDBM41628 N-(4-fluorophenyl)-4-methyl-2-(2-thienyl)thiazole-5-carboxamide::N-(4-fluorophenyl)-4-methyl-2-thiophen-2-yl-1,3-thiazole-5-carboxamide::N-(4-fluorophenyl)-4-methyl-2-thiophen-2-yl-5-thiazolecarboxamide::SR-01000759134-1::cid_7667820

SMILES N#Cc1ccc(-c2ccc(C[C@H](NC(=O)c3c(F)cc(N[C@H](C4CCOCC4)C(F)(F)F)cc3F)C(=O)O)c3cccnc23)c(Cl)c1

InChI Key InChIKey=LBVGOZDJTLSJCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 41628   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 41628BDBM41628(US11116760, Example 338)
Affinity DataEC50:  26.5nMAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
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Date in BDB:
3/23/2026
Entry Details
US Patent