BDBM418917 US10450298, Compound CHEM-US-00035::US10865195, Compound 3

SMILES C[C@@H]1CN(Cc2ccc(OCCF)cn2)CCN1C(=O)\C=C\c1ccc(Cl)cc1Cn1nnc(C)n1

InChI Key InChIKey=FMGIUSJUWXCWRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 418917   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM418917(US10450298, Compound CHEM-US-00035 | US10865195, C...)
Affinity DataIC50: 4nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM418917(US10450298, Compound CHEM-US-00035 | US10865195, C...)
Affinity DataIC50: 4.00E+3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent