BDBM418920 US10450298, Compound CHEM-US-00038

SMILES CCc1ccc(CN2CCN([C@H](C)C2)C(=O)\C=C\c2ccc(cc2Cn2nnc(C)n2)C(F)(F)F)nc1

InChI Key InChIKey=JKTYLPNIBONDLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418920   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM418920(US10450298, Compound CHEM-US-00038)
Affinity DataIC50: 1.40E+3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent