BDBM418921 US10450298, Compound CHEM-US-00039::US10865195, Compound 7

SMILES COc1cc(CN2CCN(CC2)C(=O)\C=C\c2ccc(Cl)cc2Cn2nnc(C)n2)ccn1

InChI Key InChIKey=NSZOPYNRDYEHPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 418921   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM418921(US10450298, Compound CHEM-US-00039 | US10865195, C...)
Affinity DataIC50: 13nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM418921(US10450298, Compound CHEM-US-00039 | US10865195, C...)
Affinity DataIC50: 1.30E+4nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent