BDBM419603 US10464911, Example 31

SMILES Fc1cc(ccc1CN(c1cccnc1)S(=O)(=O)N1CCNCC1)-c1nnc(o1)C(F)(F)F

InChI Key InChIKey=UVZLMQMSSNANJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419603   

TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM419603(US10464911, Example 31)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant HDAC6 using BML-AK511 as substrate incubated for 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419603(US10464911, Example 31)
Affinity DataIC50: 44nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent