BDBM419608 US10464911, Example 36

SMILES FC(F)c1nnc(o1)-c1ccc(CN(c2ccc(F)c(Cl)c2)S(=O)(=O)N2CCS(=O)(=O)CC2)nc1

InChI Key InChIKey=YSBMOVWOMZDAAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419608   

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419608(US10464911, Example 36)
Affinity DataIC50: 23nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419608(US10464911, Example 36)
Affinity DataIC50: 4.92E+4nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent