BDBM419645 US10464911, Example 69

SMILES C[C@@H]1CN(CCN1C1COC1)S(=O)(=O)N(Cc1ccc(cn1)-c1nnc(o1)C(F)F)c1cccc(Cl)c1

InChI Key InChIKey=XRMNAEKWJRAUJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419645   

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419645(US10464911, Example 69)
Affinity DataIC50: 41nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent