BDBM445953 US10669246, Example 5::US10968188, Example 5
SMILES Cc1ccncc1-c1ccc2nc(NC(=O)C3CC3)sc2c1
InChI Key InChIKey=JHDSITICBSAFEJ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 445953
Affinity DataIC50: 9nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), Bovine serum albumin (BSA) and dimethylsulfoxide (DMSO) were purchased from...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of recombinant human c-Kit assessed as luminescence using poly (4:1 Glu, Tyr) peptide as substrate incubated for 2 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:PDGFRα kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human PDGFRα (40 ng) is incubated with 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair