BDBM449019 2-{4-[(4αS,8αS)-octahydro-1H-pyrido[3,4-b][1,4]oxazin-6-yl]-2-amino-5-(3-fluoro-5-methylphenyl)pyridin-3-yl}-4-methoxy-1H-1,3-benzodiazole-6-carbonitrile ::US10696689, Compound 3-16::US11186590, Compound 3-16

SMILES COc1cc(cc2[nH]c(nc12)-c1c(N)ncc(-c2cc(C)cc(F)c2)c1N1CC[C@@H]2NCCO[C@H]2C1)C#N

InChI Key InChIKey=HMMFHOLXQZJWEC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449019   

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449019(2-{4-[(4αS,8αS)-octahydro-1H-pyrido[3,4-...)
Affinity DataEC50: <0.100nMAssay Description:On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449019(2-{4-[(4αS,8αS)-octahydro-1H-pyrido[3,4-...)
Affinity DataEC50: <0.100nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent