BDBM458389 US10744125, Example 1

SMILES COC(=O)C1CCN(CC1)c1ccc(cn1)C(=O)Nc1nc(c(s1)C#N)-c1ccccc1

InChI Key InChIKey=QZCJKDAQIZQNRF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 458389   

TargetAdenosine receptor A3(Human)
Palobiofarma

US Patent
LigandPNGBDBM458389(US10744125, Example 1)
Affinity DataKi:  103nMAssay Description:A3 Adenosine Receptor:Competitive assays were carried out by incubation of membranes from human A3 receptors transfected to CHO cells, [3H]-NECA, buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Palobiofarma

US Patent
LigandPNGBDBM458389(US10744125, Example 1)
Affinity DataKi: >500nMAssay Description:A2B Adenosine Receptor: The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Palobiofarma

US Patent
LigandPNGBDBM458389(US10744125, Example 1)
Affinity DataKi: >500nMAssay Description:Adenosine A1 Receptor: Competition assays were carried out by incubation of human recombinant membranes of adenosine receptors from hA1 receptors tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Palobiofarma

US Patent
LigandPNGBDBM458389(US10744125, Example 1)
Affinity DataKi: >1.00E+3nMAssay Description:A2A Adenosine Receptor: Competitive assays were carried out by incubation of membranes from human A2A receptors transfected to HeLa cells, [3H]-ZM241...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent