BDBM470587 US10815244, Example T

SMILES COc1cc2ncnc(Nc3ccc(O[C@H]4CO[C@@H]5[C@@H](O)CO[C@H]45)c(Cl)c3)c2cc1OC

InChI Key InChIKey=LMWDCCYLPLDXQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470587   

TargetEpidermal growth factor receptor(Human)
Rutgers The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM470587(US10815244, Example T)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Rutgers The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM470587(US10815244, Example T)
Affinity DataIC50: 100nMAssay Description:Briefly, the assay method measures ADP formed from EGFR kinase activity using luminescence derived from ATP-Luciferase detection system. Purified EGF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2021
Entry Details
US Patent