BDBM491935 (S)-5-(6-(Cyclohexylamino)-4-cyclopropylpyridin-3-yl)-N-(2-hydroxy-2-methylpropyl)-4-(2-methylpiperidine-1-carbonyl)thiazole-2-carboxamide::US10975068, Example 76

SMILES C[C@H]1CCCCN1C(=O)c1nc(sc1-c1cnc(NC2CCCCC2)cc1C1CC1)C(=O)NCC(C)(C)O

InChI Key InChIKey=HLBYSCKLZJPLFK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491935   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM491935(US10975068, Example 76 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.340nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent