BDBM492206 5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyridyl]-N-[cis-2-hydroxycyclopentyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]thiazole-2-carboxamide::US10975068, Example 347

SMILES C[C@H]1CCCN1C(=O)c1nc(sc1-c1cnc(NC(C)(C)C)cc1C(F)(F)F)C(=O)NC1CCCC1O

InChI Key InChIKey=CPDUBYPIARLIHA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492206   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM492206(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.380nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
US Patent