BDBM492220 5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyridyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]thiazole-2-carboxamide::US10975068, Example 361

SMILES C[C@H]1CCCN1C(=O)c1nc(sc1-c1cnc(NC(C)(C)C)cc1C(F)(F)F)C(=O)N[C@H]1CC[C@H](O)C1

InChI Key InChIKey=JNDJXBVCZCKKBW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492220   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM492220(5-[6-(tert-Butylamino)-4-(trifluoromethyl)-3-pyrid...)
Affinity DataKd:  0.370nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
US Patent