BDBM492310 US10975068, Example 451

SMILES O[C@H]1CCC[C@@H]1NC(=O)c1nc(C(=O)N2C3CCC2CC3)c(s1)-c1cnc(N[C@@H](C2CC2)C(F)(F)F)cc1C(F)F

InChI Key

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492310   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM492310(US10975068, Example 451)
Affinity DataKd:  0.290nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent