BDBM50046569 CHEMBL3309969

SMILES COc1cc(=O)n(cc1C(=O)NCc1ccc(F)cc1)-c1ccc(Oc2ccnc(N)c2I)c(F)c1

InChI Key InChIKey=BLNJAGORPQMNJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046569   

TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50046569(CHEMBL3309969)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50046569(CHEMBL3309969)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50046569(CHEMBL3309969)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50046569(CHEMBL3309969)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed