BDBM50083953 (Z)-4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid (0.35H2O)::CHEMBL22197::Sacchettini_7
SMILES OC(=O)C(=O)CC(=O)c1cccc(Br)c1
InChI Key InChIKey=DLBFPLZJXXVHIG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50083953
Affinity DataIC50: 800nMAssay Description:DNTB-Coupled_Enzyme_AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research and Development
Curated by ChEMBL
Glaxo Wellcome Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair