BDBM50100312 4-Imidazol-1-ylmethyl-2-(2-methoxy-phenoxy)-benzonitrile::CHEMBL25550

SMILES COc1ccccc1Oc1cc(Cn2ccnc2)ccc1C#N

InChI Key InChIKey=ZDTTWZWUUZGVNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100312   

LigandPNGBDBM50100312(4-Imidazol-1-ylmethyl-2-(2-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 340nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100312(4-Imidazol-1-ylmethyl-2-(2-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed