BDBM50129837 CHEMBL3628811

SMILES Brc1cccc(NC(=O)Nc2ccc(Oc3ncnc4sc5CCCCc5c34)cc2)c1

InChI Key InChIKey=GDCAJIUCFRKHLA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50129837   

TargetVascular endothelial growth factor receptor 2(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 17nMAssay Description:Inhibition of c-Kit (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of VEGFR3 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PDGFR-beta (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of Raf (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 8.46E+3nMAssay Description:Inhibition of Src (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129837(CHEMBL3628811)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed