BDBM50147543 2-(5-Benzooxazol-2-yl-2-methoxy-phenyl)-1,3-dioxo-indan-5-carboxylic acid::CHEMBL109471

SMILES COc1ccc(cc1N1C(=O)c2ccc(cc2C1=O)C(O)=O)-c1nc2ccccc2o1

InChI Key InChIKey=KSUQVCWZKHNZTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147543   

TargetHeparanase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50147543(2-(5-Benzooxazol-2-yl-2-methoxy-phenyl)-1,3-dioxo-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human HPSE incubated for 2 hrs using TMB peroxidase as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50147543(2-(5-Benzooxazol-2-yl-2-methoxy-phenyl)-1,3-dioxo-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo inhibitory activity against human HeparanaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed