BDBM50184864 CHEMBL203279::N-{4-[(6,7-Dimethoxy-4-quinazolinyl)oxy]phenyl}-N'-(2-methylbenzoyl)thiourea

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC

InChI Key InChIKey=PEPJPELNFRAZNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184864   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184864(CHEMBL203279 | N-{4-[(6,7-Dimethoxy-4-quinazolinyl...)
Affinity DataIC50:  623nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184864(CHEMBL203279 | N-{4-[(6,7-Dimethoxy-4-quinazolinyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed