BDBM50205140 CHEMBL3946811

SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=WDAHGVLBPINGHW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50205140   

TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of c-MET (unknown origin) using poly(Glu, Tyr)4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of c-Kit (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of FLT3 (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 95nMAssay Description:Inhibition of PDGFRalpha (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 141nMAssay Description:Inhibition of Ron (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 480nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50205140(CHEMBL3946811)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2018
Entry Details Article
PubMed