BDBM50209150 2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen-3-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-acetamide::CHEMBL245769

SMILES COCC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1csc(c1)C#CCOc1ccccc1

InChI Key InChIKey=ZKHOXOSYKYODTH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50209150   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 53nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 113nMAssay Description:Inhibition of CSF1R by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 153nMAssay Description:Inhibition of Flt3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 175nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 710nMAssay Description:Inhibition of Flt1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of Fyn by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of Lyn by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of Hck by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of Tie2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209150(2-methoxy-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen...)
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of Src by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed