BDBM50209726 (R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylamino)methyl)chroman-4-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)-propanamide::CHEMBL227870

SMILES COCCNCc1ccc2[C@@H](CCOc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=DOOVVKGISQQLQL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209726   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209726((R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylam...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209726((R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylam...)
Affinity DataIC50: 17.4nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHOD cells assessed as effect on DAK-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209726((R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylam...)
Affinity DataKi:  208nMAssay Description:Antagonist activity at rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Rabbit)
Amgen

Curated by ChEMBL
LigandPNGBDBM50209726((R)-3-(4-fluorophenyl)-N-((R)-7-((2-methoxyethylam...)
Affinity DataIC50: 1.69E+3nMAssay Description:Antagonist activity at rabbit bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed