BDBM50270430 CHEMBL4077373
SMILES C[C@H]1Cc2c(CN1C(C)=O)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc(on1)C1CC1
InChI Key InChIKey=FTKFKTZZLRFVEP-AWEZNQCLSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50270430
TargetTyrosine-protein kinase ABL1(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of human ABLMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of human LYNMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of human RETMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of human KITMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human KDR cytoplasmic domain (807 to 1356 residues) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <500nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair