BDBM50286106 CHEMBL321570::Morphinan Cyclic Imine analogue

SMILES COC12C=CC34C[C@@]1(C)[C@@H](N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286106   

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(Morphinan Cyclic Imine analogue | CHEMBL321570)
Affinity DataIC50: 0.150nMAssay Description:Compound was tested for its ability to displace [3H]DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(Morphinan Cyclic Imine analogue | CHEMBL321570)
Affinity DataIC50: 0.260nMAssay Description:Compound was tested for its ability to displace [3H]U-69593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(Morphinan Cyclic Imine analogue | CHEMBL321570)
Affinity DataIC50: 0.320nMAssay Description:Compound was tested for its ability to displace [3H]Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(Morphinan Cyclic Imine analogue | CHEMBL321570)
Affinity DataIC50: 2.60nMAssay Description:Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article